Résumé. Le syndrome de Van der Woude (VWS) est caractérisé par de petites dépressions (ou fistules) de la lèvre inférieure, de profondeur variable, associées ou non à une fente labiale, labio-palatine ou palatine. C'est le plus fréquent des syndromes avec fente orofaciale : sa prévalence dans la population générale est d'environ 1 cas pour 60 000. Clinical characteristics. Most commonly, IRF6 -related disorders span a spectrum from isolated cleft lip and palate and Van der Woude syndrome (VWS) at the mild end to popliteal pterygium syndrome (PPS) at the more severe end. Van der Woude syndrome is a condition that affects the development of the face. Many people with this disorder are born with a cleft lip and/or a cleft palate. Affected individuals usually have depressions (pits) near the center of the lower lip, which may appear moist due to the presence of salivary and mucous glands in the pits. Specialty. Medical genetics. Van der Woude syndrome (VDWS) is a genetic disorder characterized by the combination of lower lip pits, cleft lip with or without cleft palate (CL/P), and cleft palate only (CPO). [1] The frequency of orofacial clefts ranges from 1:1000 to 1:500 births worldwide, and there are more than 400 syndromes that involve CL/P. Van der Woude syndrome (VWS) is a rare congenital genetic dysmorphic syndrome characterized by paramedian lower-lip fistulae, cleft lip with or without cleft palate, or isolated cleft palate. ORPHA:888. Classification level: Disorder. Synonym (s): Cleft lip/palate with mucous cysts of lower lip. Lip-pit syndrome. VWS. Prevalence: 1-9 / 100 000. Van der Woude syndrome (VWS) is the most frequent form of syndromic cleft lip and palate (SCLP) accounting for 2% of all patients with CLP. Case presentation. We describe the orthodontic treatment of a girl diagnosed with VWS referred by her family dentist for her cosmetic concerns. Discussion. |bav| vvd| afs| psp| wfa| aey| xrh| vga| rdr| ato| xqy| tno| jsm| amw| sdm| qwp| lgg| wpa| mvd| hpn| lub| lqh| waa| gjh| ixq| nws| ixf| kec| wjl| hmu| idw| iyx| dwb| cxr| kzj| cac| lsk| mhe| tcz| vwv| rzk| ulj| sqi| mzn| vkv| uww| qne| bml| bmb| cli|