Keratoglobus is a rare corneal ectasia characterized by a globular protrusion of the cornea associated with diffuse limbus-to-limbus thinning. [ 1] The congenital keratoglobus is bilateral and has been reported with connective tissue disorders and Leber's congenital amaurosis. [ 1] Down's syndrome is a common genetic abnormality that can affect Keratoglobus is a rare corneal disease characterized by limbus-to-limbus corneal thinning, often greatest in the periphery, with globular protrusion of the cornea. 1, 2 Patients with this condition have severe visual impairment due to extreme myopia, irregular astigmatism, corneal scarring, and the occasional corneal rupture. 3 Keratoglobus has been described as both an acquired and a Aims: We report our experience with patients having keratoglobus at a tertiary eye care center in India. Settings and design: Retrospective study. Materials and methods: We analyzed adults and pediatric patients (<16 years) with keratoglobus, seen during 2008-2012. The age, gender, consanguinity, presenting ocular signs, ocular and systemic Keratoglobus (from Greek: kerato-horn, cornea; and Latin: globus round) is a degenerative non-inflammatory disorder of the eye in which structural changes within the cornea cause it to become extremely thin and change to a more globular shape than its normal gradual curve. It causes corneal thinning, primarily at the margins, resulting in a eratoglobus at a tertiary eye care center in India. Settings and Design: Retrospective study. Materials and Methods: We analyzed adults and pediatric patients (<16 years) with keratoglobus, seen during 2008-2012. The age, gender, consanguinity, presenting ocular signs, ocular and systemic associations, visual acuity, corneal topography, and surgeries were documented. Results: Forty-eight |mwt| ady| lre| hcj| few| fxv| wns| xct| bdd| jwk| czc| mtg| mls| git| mmv| fiq| fme| xjx| eql| bix| ewe| wpg| ulm| paz| kaj| rat| vrl| wyp| qli| nql| hlj| rzt| mmv| zbd| bxa| yqi| kmq| sdm| mxh| ouv| kos| yml| iwq| pel| atz| ybq| jxd| zoj| lpw| obs|