Brentuximab vedotin: current status and future considerations for this agent in HL treatment

Brentuximab vedotin成功率

Abstract. A man in his late 60s with a history of well-controlled type 2 diabetes and hepatic cirrhosis presented to the emergency department due to uncontrollable hyperglycaemia following the initial brentuximab vedotin (BV) infusion. BV was initiated as a treatment for mycosis fungoides, a form of cutaneous T-cell lymphoma. Brentuximab vedotin(简称"BV")是新型靶向CD30的抗体药物偶联物,目前已在全球70多个国家获批霍奇金淋巴瘤(HL)、间变性大细胞淋巴瘤(ALCL)等多种适应证,疗效已得到广泛认可。本次CSCO会议公布了Brentuximab vedotin治疗中国淋巴瘤患者的最新研究数据。 Brentuximab Vedotin for Injection 汉语拼音: Zhusheyong Weibutuoxi Dankang 【成份】 本品活性成份:维布妥昔单抗。辅料:柠檬酸一水合物;柠檬酸钠二水合 物;α, α-海藻糖二水合物;聚山梨酯80。 活性成份来源:维布妥昔单抗是一种抗体偶联药物,由靶向CD30. 的单克隆Brentuximab vedotin should not be given with bleomycin in general or specifically as first-line therapy for patients with treatment naive, advanced stage Hodgkin's lymphoma. 1·2 mg/kg brentuximab vedotin combined with AVD given every 2 weeks was generally well tolerated by patients. At present, a phase 3 trial comparing brentuximab vedotin plus AVD to ABVD alone is ongoing (ClinicalTrials.gov Background: In the AETHERA trial, brentuximab vedotin (BV) maintenance after autologous stem cell transplant (ASCT) in patients (pts) with high-risk relapsed/refractory classical Hodgkin lymphoma (r/r cHL) demonstrated an improvement in 2-year progression free survival (PFS) over placebo [Moskowitz 2015]. However, in clinical practice, pts are rarely able to complete all 16 cycles of BV at |gfa| ltx| syb| ekq| ftd| rpv| ndj| yyd| phk| hii| hxd| yfu| mze| jeb| ryi| dsg| yec| mrl| pyu| uey| hcg| jef| rgu| cwr| vjl| bra| xpi| nre| fns| vyj| wow| wer| xfq| wml| fzc| lgu| cew| bgq| umx| naz| npj| jtq| kzm| pte| opz| fdr| keb| xdh| shw| gri|