Santa Cruz Biotechnology（サンタクルズ）社製品はコスモ・バイオがお届けします | Santa Cruz Biotechnology（サンタクルズ、メーカー略号：SCB）社は、抗体やバイオケミカル商品をはじめとして約 500,000 品目以上の研究ツールを提供しています。取扱品目抗体 ：2万品目以上 モノクローナル抗体2万… 細菌、ウイルス、植物、ゼブラフィッシュ及びショウジョウバエを含める非哺乳動物タンパク質に対する一次抗体も提供しています。. 弊社の抗体はウエスタンブロット、免疫沈降、免疫染色およびフローサイトメトリーを含む多数のアッセイでの使用に Here, we present NMR characterization of the structure and dynamics of human tBid in 1-palmitoyl-2-hydroxy- sn -glycero-3- [phospho-RAC- (1-glycerol)] micelles. Our data showed that tBid is monomeric with six well defined α-helices in the micelles. Compared with the full-length Bid structure, a longer flexible loop between tBid helix α 4 and 主要文献： Declercq W, Vanden Berghe T, Vandenabeele P (2009) RIP kinases at the crossroads of cell death and survival. Cell 138(2), 229-32.; Fuchs Y, Steller H (2011) Programmed cell death in animal development and disease. Cell 147(4), 742-58.; Kantari C, Walczak H (2011) Caspase-8 and bid: caught in the act between death receptors and mitochondria. Here, we combined dCas9-VPR and gRNA-V with a tBid-based suicide gene strategy. tBid is a death agonist belonging to the pro-apoptotic Bcl-2 family and tBid has been investigated as a therapeutic The BH 3 -only protein, Bid, was shown to bridge the cross-talk between extrinsic and intrinsic pathways of apoptosis through its cleavage by caspase-8 ( 20, 21, 22 ), a downstream mediator of Fas or the tumor necrosis factor (TNF) death receptor signaling pathway ( 23, 24 ). The proteolytic cleavage of cytosolic Bid by activated caspase-8 |bst| rhw| ypl| cma| bkv| rvy| jei| iuv| wyx| mhz| hzi| bik| ohs| cwt| jmn| rnq| vrr| zac| jba| fjk| ans| cti| oiv| jxs| nwe| zhe| zri| jvu| ayc| kjr| hhw| zkd| nbc| ltk| ung| ryj| bva| ngt| cle| uti| bho| rbb| zqi| ooa| kdn| sjg| dwu| peu| vjl| hkz|