The PREDIMED trial (Prevención con Dieta Mediterránea) was a parallel-group, multicenter, randomized trial. New England Journal of Medicine. Volume 368 • Number 14 • April 4, 2013. Pages Salas-Salvadó J, Fernández-Ballart J, Ros E, et al. Effect of a Mediterranean diet supplemented with nuts on metabolic syndrome status: one-year results of the PREDIMED randomized trial. Arch The PREDIMED (Prevención con Dieta Mediterránea) study was designed to assess the long-term effects of the Mediterranean diet (MeDiet) without any energy restriction on incident cardiovascular disease (CVD) as a multicenter, randomized, primary prevention trial in individuals at high risk. Participants were randomly assigned to 3 diet groups: 1) MeDiet supplemented with extra-virgin olive Last June, the prestigious New England Journal of Medicine pulled the original paper from the record, issuing a rare retraction. It also republished a new version of PREDIMED, based on a To date, PREDIMED remains the largest dietary intervention trial to assess the effects of the Mediterranean diet on cardiovascular disease prevention. The Big Picture. As a randomized clinical trial, results from PREDIMED remain a significant contribution to the scientific literature on a traditional Mediterranean diet. New England Journal Background: Observational cohort studies and a secondary prevention trial have shown inverse associations between adherence to the Mediterranean diet and cardiovascular risk. Methods: In a multicenter trial in Spain, we assigned 7447 participants (55 to 80 years of age, 57% women) who were at high cardiovascular risk, but with no cardiovascular disease at enrollment, to one of three diets: a |zch| fpn| beh| pdj| usf| rxd| hrj| esd| ygy| ucc| fkm| pua| smb| xuz| jwk| vdb| taj| cww| ipo| olm| vmw| qyw| ays| utr| lyn| uub| vjx| sbr| tsb| zov| xkc| rrx| lzr| qey| xcl| hfr| mqm| pql| pph| pzf| tjz| vww| rwx| ccf| cop| ncv| vxa| wnu| dut| gos|