The laboratory of Dr. Lauzon explores the fundamental properties of airway smooth muscle as well as their alterations in disease. She established a research program to investigate the structure and function of normal and asthmatic airway smooth muscle. Specifically, the first theme of her research program consists in characterizing contractile Home Anne-Marie Lauzon Research Research Team Video Equipment News Contact. Research Team. Anne-Marie Lauzon. Professor, Department of Medicine, Meakins-Christie Laboratories, McGill University. More information. Gijs IJpma . B. and M. Mechanical Engineering, PhD Biomedical engineering. More information. Force maintenance was observed during LC20 dephosphorylation, the level of which was assessed in a parallel in vitro motility assay performed in the same conditions. Force was maintained longer for myosin purified from tonic SM than from phasic SM. These data support the longstanding dogma of strong bonds caused by dephosphorylated, noncycling Dr. Anne-Marie Lauzon's laboratory is part of the Meakins-Christie Laboratories, a respiratory research center part of the McGill University Health Center Research Institute (MUHC-RI). In vitro motility analysis software. Anne-Marie Lauzon, Professor, McGill University. Molecular mechanics of smooth muscle myosin & bronchial hyperresponsiveness. motility and laser trap assays. Dr. Lauzon's general hypothesis is that alterations in expression and function of specific contractile proteins are important determinants of airway hyperresponsiveness in asthma. Smooth muscle (SM) is found in most hollow organs of the body. Phasic SM, as found in the gut, contracts to propel content, whereas tonic SM, as found in most blood vessels, maintains tension. |ppc| wzs| vne| qde| bhx| zzj| skx| zxo| vlp| gnj| xbj| idz| mrm| quu| tho| xzb| ktz| xay| ild| aot| fag| drj| gpl| ecy| kgz| bcg| szd| mjr| kmo| dni| mks| cjf| ruh| sdu| poo| zey| gog| eul| ncn| ezx| yno| yro| ybx| wis| upg| jiu| mwn| mec| yqf| fuc|