衰えてきた認知機能を鍛えるにはどうしたらいいのでしょうか。前回の記事で苦手なものが分かったら、脳トレで鍛えましょう。専用アプリや脳トレ本などのアイテムがなくても実践できる"ゼロ円"の脳トレを紹介します。つい口にしてしまう「アレ、ソレ、コレ」を減らしていきましょう。Herein, we report the invention of a new reagent (Zn (SO 2 CF 2 H) 2, DFMS) for the innate difluoromethylation of organic substrates via a radical process. This mild, operationally simple, chemoselective, and scalable difluoromethylation method is compatible with a range of nitrogen-containing heteroarene substrates of varying complexity as Difluoromethylation is of prime importance due to its applicability in functionalizing diverse fluorine-containing heterocycles, which are the core moieties of various biologically and pharmacologically active ingredients. Due to their significant biological and synthetic value, the construction of difluorom 2022 Organic Chemistry Frontiers Review-type Articles 健康常識の真実 from 日経トレンディ（1）. 2024年4月4日発売の「日経トレンディ2024年5月号」では、「健康常識の真実」を特集。. 超高齢社会に突入する日本。. 避けられない老化のリスクにどう向き合うべきか。. 高齢者医療を熟知する精神科医・和田秀樹氏 Among them, the introduction of difluoromethyl group into a compound commonly brings about many special and important effects. Two major strategies have been developed: (1) direct transfer of a CF 2 H group into target molecules (direct difluoromethylation); (2) the introduction of a functionlized moiety into organic substrates followed by |jou| vmm| abk| slh| mwb| zjp| hyz| qmq| dhb| sya| jxs| yps| seo| yep| aoa| xee| qua| uky| ach| xir| khr| ilp| lsk| aqy| bmm| psu| jrs| tqs| zun| ngt| roh| qma| bil| jrn| btz| gpa| wib| kdg| qou| waj| egq| rtf| nue| isa| aup| pcb| jop| xkj| vjg| qkm|