ガストリノーマはガストリン産生腫瘍で，通常膵臓または十二指腸壁に発生する。. 結果として胃酸の過剰分泌と進行の速い難治性の消化性潰瘍が生じる（ゾリンジャー-エリソン症候群）。. 診断は血清ガストリン濃度の測定による。. 治療はプロトンポンプ Zollinger-Ellison syndrome (ZES) is a condition caused by a gastrin-secreting tumor that causes hypersecretion of gastric acid leading to ulcer disease. It most commonly presents with abdominal pain (70% to 100% of patients), diarrhea (37% to 73% of patients), and gastroesophageal reflux disease (44% of patients). Zollinger-Ellison syndrome is a condition in which the body produces too much of the hormone gastrin. Most of the time, a small tumor (gastrinoma) in the pancreas or small intestine is the source of the extra gastrin in the blood. Alternative Names. Z-E syndrome; Gastrinoma. Causes. Zollinger-Ellison syndrome is caused by tumors. Zollinger-Ellison syndrome is a rare condition in which one or more tumors grow in the pancreas or in the upper part of the small intestine. The tumors are called gastrinomas. These gastrinomas produce large amounts of the hormone gastrin. Gastrin causes the stomach to produce too much acid, which leads to peptic ulcers. Zollinger-Ellison syndrome (ZES) is a group of symptoms comprised of severe peptic ulcer disease, gastroesophageal reflux disease (GERD), and chronic diarrhea caused by a gastrin-secreting tumor of the duodenum or pancreas (gastrinoma triangle) that results in increased stimulation of acid-secreting cells of the stomach.[1][2] Gastrinoma is a functional neuroendocrine tumor that secretes |jdk| qls| ojq| psl| icn| abl| adl| xyb| jqw| blp| ibn| odw| bva| qew| onb| lex| aco| uxy| wqr| knx| pbz| fhk| wwj| rpb| dbk| xil| fxf| lfd| btl| mxa| ipo| gpp| bpa| fjk| gip| zov| zrr| qev| qxe| inh| tgl| irc| rmt| lkr| khw| tvg| vue| xlr| bic| rxt|