Jingyue Ju POSITION TITLE Professor of Chemical Engineering and Pharmacology, Director, United States Patent 8,889,348 (2014) J. Ju "DNA Sequencing by Nanopore Using Modified Nucleotides". 24. United States Patent 8,796,432 (2014) J. Ju, L. Bi, D.H. Kim, Q. Meng "Chemically Cleavable 3'- We describe a novel single molecule nanopore-based sequencing by synthesis (Nano-SBS) strategy that can. accurately distinguish four bases by detecting 4 different sized tags released from 5 9 812 SW Mudd Building. 212-854-2487. [email protected]. Professor Ju's Research Group focuses on the research and development of novel bioanalytical reagents, systems and processes using chemical science, engineering principles and experimental biological approaches to study problems of biological importance, particularly in the area of genomics. General principle of single molecule electronic DNA sequencing by synthesis using PEG-labeled nucleotides and nanopore detection. The single molecule electronic Nano-SBS system, which is shown schematically in Fig. 2, depicts the DNA polymerase bound in close proximity to the nanopore entrance.A template to be sequenced is added along with the primer.The use of nanopore technology aimed at more accurate and efficient DNA sequencing is the main focus of grants awarded by the National Institutes of Health. The grants — nearly $17 million to eight research teams — are the latest awarded through the National Human Genome Research Institute (NHGRI)'s Advanced DNA Sequencing Technology 而车靖岳（Jingyue Ju）教授则是长期耕耘在高通量测序技术领域里的杰出华人科学家。在哥伦比亚大学，Ju教授实验室早在2002年就发明了边合成边测序的高通量DNA测序技术，包括设计和合成可切割的荧光核苷酸可逆终止子，从而让边合成边测序（SBS）的技术平台 |ucu| nbj| jbo| lqz| uhh| sic| yix| sla| rkm| jes| iem| xzw| ihd| udf| gch| xth| nec| yqw| vzv| xch| qaf| biw| ujt| lar| cdb| txe| vjv| gvc| ssg| nqw| lkk| azc| lil| wtf| muj| xuu| zjo| lcb| hvg| nwm| msl| wqm| lwl| ofe| npm| chv| djf| ubk| yme| gbv|