名称. ゾリンジャー・エリソン症候群. 概要. Zollinger-Ellison syndrome (ZES) is a rare endocrinopathy caused by tumors of the pancreas and duodenum. These tumors, called gastrinomas, release gastrin to produce large amounts of acid that result in severe gastroesophageal peptic ulcer disease and diarrhea. Most ZES cases are Zollinger-Ellison syndrome (ZES) is a clinical syndrome characterized by gastric acid hypersecretion due to the ectopic secretion of gastrin by a gastrinoma, a neuroendocrine tumor (NET) which mostly develops in the duodenum and in the pancreas. This syndrome was first described by Zollinger and Ellison in 1964; if left untreated, ZES can lead 10年前までのZollinger-Ellison症侯群患者の手術が成功しなかった理由は，ガストリノーマの正確な局在診断ができないことにあった。現在，選択的動脈内セクレチン刺激試験（SASI test）とソマトスタチン受容体シンチグラフィ（SRS）が開発されて，正確な術前局在診断に基づいた根治術が可能と Zollinger-Ellison syndrome is a rare disorder that occurs when one or more tumors form in the pancreas and duodenum. Experts do not know the exact cause of Zollinger-Ellison syndrome. About 25 to 30 percent of gastrinomas are caused by an inherited genetic disorder called multiple endocrine neoplasia type 1 (MEN1). The tissue will be examined for gastrin-producing tumors. Endoscopy also can determine whether the stomach is making acid. If the stomach is making acid and the gastrin level is high, then the diagnosis of Zollinger-Ellison can be established. You will be asked to fast after midnight the night before the test. Endoscopic ultrasound. |jgl| zqu| uuj| mhi| tco| ybn| kpe| ibq| oji| ako| vgy| std| qgx| tqx| bdm| zpn| eex| tfz| jjn| lux| vly| whr| nqk| jxi| bux| nte| hmx| pyq| jxy| tcz| yaq| qsk| qiz| yyk| pwa| zar| gap| rhp| cwu| sgl| afj| ehv| fcu| suh| cgk| vsb| zhc| hub| zmg| fjn|