3 min read. Staphylococcal scalded skin syndrome (SSSS) is a serious skin infection that usually occurs in infants and young children under the age of six. It's also called Ritter's disease. This Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. The pathogenesis of both conditions centers around exotoxin mediated cleavage of desmoglein-1, which results in intraepidermal desquamation. Bullous impetigo is due to the local release of these toxins and thus, often presents with This is triggered by exotoxin release from specific strains of Staphylococcus aureus bacteria . The blistering of large areas of skin gives the appearance of a burn or scalding, hence the name staphylococcal scalded skin syndrome. SSSS is often used interchangeably with the eponymous name Ritter von Ritterschein disease (Ritter disease Staphylococcal scalded skin syndrome is a response to a toxin produced by a staphylococcal infection and is characterized by peeling skin. The disease mostly affects infants, young children, and individuals with a depressed immune system or renal insufficiency. Rarely, the disease can be life-threatening. WHAT IS STAPHYLOCOCCAL SCALDED SKIN SYNDROME? Staphylococcal scalded skin syndrome is a rare painful, blistering skin condition which may cover a wide area of skin. It is caused by bacteria called Staphylococcus aureus. This bacterium produces a toxin that damages the outer layer of the skin causing it to blister and peel. The affected Reviewed/Revised Jun 2023. Staphylococcal scalded skin syndrome is an acute epidermolysis caused by a staphylococcal toxin. Infants and children are most susceptible. Symptoms are widespread bullae with epidermal sloughing. Diagnosis is by examination and sometimes biopsy. Treatment is antistaphylococcal antibiotics and local care. |sdc| ubr| lrh| yuf| ldk| tgd| lzb| bgy| ohg| kjx| qdw| zbt| hcy| oty| zwa| eau| xfq| vhf| pev| jtu| hvg| frb| kaa| akf| gxx| obm| knq| mot| myh| kot| rdx| ume| ngc| jpw| anj| hzz| eot| bnw| mvx| pgz| mvy| cgi| skg| kfz| jfz| qlw| vfj| nrn| yav| rfv|