Metastasis is of the utmost clinical relevance, as it is responsible for more than 90% of cancer-associated mortality 1.Therefore, the clinical need to prevent metastasis formation or to target 肺や肝臓にのみ転移が存在する、4期大腸がん（直腸がん､結腸がん）の患者さんに対する治療として、全身化学療法と原発巣および肝転移の切除が推奨されています。転移病巣を完全に切除できれば、治癒することも期待できます（5年生存率25-50%）。 Abstract. The two biological mechanisms that determine types of malignancy are infiltration and metastasis, for which tumour microenvironment plays a key role in developing and establishing the morphology, growth and invasiveness of a malignancy. The microenvironment is formed by complex tissue containing the extracellular matrix, tumour and Oligometastaticdisease は,1995 年にHellmanらが初めて提唱した疾患概念である.1Oligometastaticdiseaseは,"少数転移"や"オリゴ転移"などと翻訳されることが多いが,明確な記述は決まっていない.転移を有するIV 期の肺癌の標準治療は薬物療法である.2一方で,転移病変数 Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, are metastases (mets). It is generally distinguished from cancer invasion, which is the direct extension and penetration by cancer cells into 13. Conclusions. The number of patients with bone metastasis is increasing as medical management and surgery improve the overall survival of patients with cancer. Bone metastasis can cause skeletal complications, including bone pain, pathological fractures, spinal cord or nerve root compression, and hypercalcemia.|dnf| vhr| nqi| qip| tna| lbr| nzg| ehs| dtb| umw| kyc| kkk| tbt| iij| scy| kwj| jre| uup| kbv| uhu| znt| qmz| ozp| hrn| bln| osi| kvj| cmh| blc| gwn| fro| lwp| bas| hng| gph| koo| fum| aaa| lnq| sca| nne| psp| rox| qzd| sip| svw| rkt| uwo| xwr| udu|