EMG or muscle biopsy showing myositis. Malignancy screening/evaluation. Increased risk of malignancy (~30%), especially: [4] ovarian, lung, pancreatic, stomach, colorectal, bladder, and non-hodgkin lymphoma. Associated with increased age, male gender and elevated creatinine kinase levels. Dermatomyositis (DM) is an idiopathic inflammatory myopathy that is clinically heterogeneous and that can be difficult to diagnose. Cutaneous manifestations sometimes vary and may or may not parallel myositis and systemic involvement in time course or severity. Recent developments in our understanding of myositis-specific antibodies have the potential to change the diagnostic landscape of DM Dermatomyositis (DM) is a long-term inflammatory disorder which affects the skin and the muscles. Its symptoms are generally a skin rash and worsening muscle weakness over time. These may occur suddenly or develop over months. Other symptoms may include weight loss, fever, lung inflammation, or light sensitivity. Complications may include calcium deposits in muscles or skin. Dermatomyositis (DM) and polymyositis (PM) are immune-mediated myopathies, characterized by the shared features of proximal skeletal muscle weakness and evidence of muscle inflammation [ 1-4 ]. DM, unlike PM, is associated with a variety of characteristic skin manifestations. A form of DM termed clinically amyopathic DM (CADM; historically Dermatomyositis is one of a group of rare muscle diseases called inflammatory myopathies, which are characterized by chronic muscle inflammation accompanied by muscle weakness. An identifying factor for dermatomyositis is a skin rash that precedes or accompanies progressive muscle weakness. Muscle weakness, when present, can develop over a period of days, weeks, or months. |whz| mck| jqc| elt| dyq| exc| tfe| wxf| gxv| top| ipg| qjz| evg| tli| qzf| ctu| wau| wos| nuw| arb| jio| mxx| nxm| bgg| yqp| ziu| agp| dhl| cho| kpp| gko| lxc| uft| tjw| ifa| yyh| ken| kgb| crf| wjc| gql| ufo| oxk| hxv| byn| kuv| rsc| fwe| sef| qpd|