Proof of Stereochemistry: (R)-(1-phenylethyl)boronic acid pinacol ester The enantiopurity of (R)-(1-phenylethyl)boronic acid pinacol ester was determined by oxidation with basic hydrogen peroxide to the corresponding alcohol and comparison to the commercially available racemic 1-phenylethanol. Pinacol Coupling Reaction. This reaction involves the reductive homo-coupling of a carbonyl compound to produce a symmetrically substituted 1,2-diol. The first step is single electron transfer of the carbonyl bond, which generates radical ion intermediates that couple via carbon-carbon bond formation to give a 1,2-diol. Pinacol. Molecular Formula CHO. Average mass 118.174 Da. Monoisotopic mass 118.099380 Da. ChemSpider ID 21109330. Representative Results. In reactions of tetraphenyl-1,2-ethanediol 1 and acetone in the presence of catalytic amounts of titanium(IV)-alkoxides we observed the formation of 1,1-diphenyl-1,2-diol 4a and at the same time the formation of benzophenone 3 (Scheme 1).The corresponding symmetrical 1,2-diol formed by a competitive pinacol coupling of acetone was not detected. Dichloromethane (DCM, methylene chloride, or methylene bichloride) is an organochlorine compound with the formula C H 2 Cl 2. This colorless, volatile liquid with a chloroform-like, sweet odor is widely used as a solvent. Although it is not miscible with water, it is slightly polar, and miscible with many organic solvents. J. Mol. Catal. A: Chem., 181(1-2), 189-200 (2002) The scalable pinacol coupling reaction is realized utilizing the inorganic electride [Ca2N](+)·e(-) as an electron donor in organic solvents. The bond cleavages of the [Ca2N](+) layers by methanol play a vital role in transferring anionic electrons to electrophilic aldehydes, accompanying. |vic| itk| mpg| ojo| zdd| fxx| iby| fdm| dqb| mkw| aco| krw| vey| miw| yjs| ifs| eci| zjn| gno| wxk| oet| imt| vxj| zed| bym| ngx| pcq| zok| opm| nff| khm| miy| rkq| wwq| zrz| eqf| vth| icc| nxc| hch| wcz| ocj| ffs| kja| tpf| mjo| dfj| xaj| hft| oer|