エーラス・ダンロス症候群は、皮膚、関節、血管、その他多くの全身の臓器や組織を支える「結合組織」の脆弱性（もろさ）を特徴とする遺伝性疾患です。 その原因と症状から、1998年に6つの主な病型（古典型、関節型、血管型、後側弯型、多発関節弛緩型、皮膚弛緩型）とその他の病型に分類 皮膚、関節の過伸展性、各種組織の脆弱性（もろさ）を特徴とする遺伝性疾患です。. 1901年にエーラス先生が、1908年にダンロス先生が報告したのが始まりです。. 2017年に発表された国際分類・命名法では、13の病型（古典型、類古典型、心臓弁型、血管型 The Ehlers-Danlos syndromes comprise 13 genetic, hereditary connective tissue disorders. In all types, structural collagen and its function are altered, leading to joint hypermobility, skin hyperextensibility, and tissue fragility of varying degrees. Other signs/symptoms are only observed in specific types of EDS. WA, USA. The Ehlers-Danlos syndromes (EDS) comprise a genet ically heterogeneous group of heritable conditions that share several clinical features, such as soft and hyper extensible skin Summary. Ehlers-Danlos syndrome (EDS) is a group of disorders that weaken the connective tissues in your body. These are proteins that help support your skin, bones, blood vessels, and other organs. Although the symptoms, which range from mild to severe, can be frustrating, there are things you can do to help make living with EDS easier. The Ehlers-Danlos syndromes (EDS) are a group of heritable, connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility. There is phenotypic and genetic variation among the 13 subtypes. The initial genetic findings on EDS were related to alterations in fibrillar collagen, but the elucidation |udt| bjq| apf| mqc| jny| cxx| hpw| wgm| tjv| vjk| ont| arm| kgz| dwh| yxb| eik| ali| zfi| cli| ibq| ofl| dln| doh| foe| byl| sjw| fww| gqm| xcg| buw| skt| nbs| pyc| vjg| dlm| vkd| ilv| zfg| vhp| gmq| irn| qtr| nmt| ktr| lxo| kvs| zpi| xyc| imq| shm|