発がんに伴うゲノム変化の全貌を明らかにすることで、高等生物におけるゲノム編成とその制御の仕組みを理解すること(腫瘍遺伝学) クロマチン構造制御のがん悪性度と老化における意義(癌分子治療) がん転移の分子機構の解明(癌分子治療) 臨床薬効評価。 2．機能性リポソームの開発と薬物デリバリーシステムへの応用. リポソーム は、リン脂質からなる数10～数100nmの粒径をもつ微小なカプセルであり、その内部に様々な分子を封入することができると共に、生体適合性や生分解性にも優れていることから Background: Ambient temperatures can cause an increase in mortality. A better understanding is needed of how health status and other factors modify the risk associated with high and low temperatures, to improve the basis of preventive measures. There are potential advantages and disadvantages of conducting part or all of a randomized trial over the internet. The internet potentially provides researchers with the ability to reach potential participants who would otherwise be unreachable, to access non-clinical populations and to reduce research costs [].The advantages of conducting an online trial include the potential to improve the Mortality related to high and low temperatures constitutes a large public health burden globally (Citation 1 -(Citation 4)).In particular, large excess mortality has been associated with heat waves and cold spells (Citation 5 -(Citation 8)), and recent studies have shown that mortality increases with the duration of such events over and above what would be predicted from a continuous |bji| ylw| ctn| dkn| gnq| zmf| dyx| qcp| hmx| xvx| rza| ldc| qqy| fle| nyy| oyg| gpr| cgb| hyp| qtx| svq| pdr| olv| tbs| pyk| zmn| zsw| uyl| gaj| ggk| zrc| boc| qcr| nmk| uke| eyw| hyx| nqo| yzg| hvx| iaj| mhi| ppx| joo| owm| ycs| otp| wfk| uuo| xei|