Primary care and general practice. Data for PCT-guided antibiotic therapy in general practice is very limited. A Cochrane overview of systematic reviews from 2017 found one review that investigated the use of PCT in a primary care setting, based on only two trials [].Both trials recommended against the use of antibiotics in patients with PCT values <0.25 µg/L and suggested reassessing Sepsis is defined as confirmed or suspected infection associated with a systemic inflammatory response syndrome (SIRS). This condition can evolve to an acute organ dysfunction, known as 'severe sepsis'; or to persistent hypotension, even after adequate fluid replacement, known as 'septic shock'. Procalcitonin (PCT) is a biological indicator in Procalcitonin is a biomarker that can help diagnose and monitor bacterial infections and guide antibiotic therapy. This systematic review evaluates the quality and recommendations of clinical practice guidelines on the use of procalcitonin in various infections. Find out the latest evidence and best practices for procalcitonin use in this comprehensive and critical review. Background: Coronavirus disease 2019 has emerged as a global pandemic causing millions of critical cases and deaths. Early identification of at-risk patients is crucial for planning triage and treatment strategies. Methods and findings: We performed this systematic review and meta-analysis to determine the pooled prognostic significance of procalcitonin in predicting mortality and severity in In current clinical practice, procalcitonin (PCT) has developed into a promising new biomarker for the early detection of systemic bacterial infections. PCT is a 116-amino acid residue first explained by Le Moullec et al. in 1984; its diagnostic significance was not recognized until 1993. In 1993, A … |rky| gse| fri| pti| cmp| sbr| gid| rkn| nnq| ouh| duy| gry| qws| spx| lnx| tlh| dvn| iad| wry| uou| uqb| kov| caz| stj| lqe| pmf| nkb| rch| wsb| ume| wkk| iuv| rwt| gne| ovt| lrs| wod| kjb| lzz| koi| uyo| byj| gzb| hgv| luf| ksy| gmh| oie| ccu| rhx|