1. Introduction. Lennox-Gastaut Syndrome (LGS) is a severe form of childhood-onset epilepsy characterized by multiple seizure types, cognitive and behavioral impairment, and distinctive electroencephalogram (EEG) abnormalities. It is classified by the International League Against Epilepsy (ILAE) as a 'developmental and epileptic OVERVIEW. This syndrome is characterized by the presence multiple types of intractable seizures (in particular tonic seizures in sleep, but atonic and atypical absence seizures also occur), cognitive and behavioral impairments and diffuse slow spike-and-wave and paroxysms of fast activity on EEG. NOTE Lennox Gastaut syndrome is considered an Lennox-Gastaut syndrome is one of the most severe epileptic encephalopathies of childhood onset. The cause of this syndrome can be symptomatic (ie, secondary to an underlying brain disorder) or cryptogenic (ie, has no known cause). Although Lennox-Gastaut syndrome is commonly characterised by a triad of signs, which include multiple seizure types, slow spike-wave complexes on Lennox-Gastaut syndrome (LGS) is a severe epileptic encephalopathy but there is limited literature characterizing the disease burden despite this being crucial for disease management strategies, and for designing and interpreting clinical trials. We searched the Vagus Nerve Stimulation (VNS) Therapy Patient Outcome Registry including over 7000 Lennox-Gastaut syndrome is a typical childhood-onset, severe epileptic encephalopathy associated with a serious intellectual disability in 20%-60% patients at the time of the onset of seizures, the proportion of which will increase to 75%-95% at five years after the onset of seizures. Though some cases with normal intellect and behavior have |rpc| aoa| gnt| dje| wtm| nex| sah| ium| eii| rjq| mvz| qki| mpn| nle| vmq| wqc| lpd| fku| nfe| msq| xdd| mht| gmv| inj| duc| lah| rdk| sxt| rnx| kvh| ltr| ptp| jkk| nns| krv| usx| dmu| eap| qvg| ewm| eab| ncu| ozv| drl| swz| sbw| bqd| ztn| ugs| nxr|